Our Science
The Epigenetic Edge: Unlocking the Power of AGELESS™ Technology
Idunn's Apple harnesses the transformative power of AGELESS™ (AI-Guided Epigenetic-Linked Eco Skincare System) Technology to revolutionize anti-aging skincare. By leveraging cutting-edge epigenetic science with artificial intelligence, our products tap into the cellular narrative of the skin, influencing the expression of youth-defining genes for a visibly rejuvenated appearance.
Big Data Analysis
Data from over 20,000 skincare products were evaluated for composition, and safety levels.
Epigenetic Test Data
We test for skin quality including skin aging levels using the peer reviewed MethylAge process, which are obtained with next-generation sequencing of skin gene-specific epigenetic changes.
Functional Bioinformatics
More than 200,000 different ingredients used in our skincare product database were categorized for their function and impact on the epigenetic level.
Hazard Classification
Safety levels were determined through a scoring system by assessing ingredient impact for severity of detrimental side effects to the skin (EWG criteria as reference).
Skintelli Field Tested
In addition to our lab-grade analysis, we leveraged aging-associated antioxidant testing from SKINTELLI, a provider of consumer self-tests, to visually prove the anti-aging effects of our formulated products.
AI Modeled Optimization
All data sets were trained via artificial intelligence and the most optimal combination of ingredients were selected for the best formulations to achieve ideal skin anti-aging efficacy.
Proven Aging Deceleration
Lab studies were conducted on subject that used no skincare application versus applying Idunn’s Apple Age-Defying Serum and Age-Defying Cream on face daily for 4 weeks. The peer-reviewed methylation-based aging clock method was then used to assess resulting epigenetic skin age in DNA. An average of 8.5 years were reduced at the epigenetic aging level when using the Idunn's Apple regimen.
SERUM
Idunn's Apple Age-Defying Serum was compared against 6 other popular top brands based on performance index (Function/Hazard Score).
Lotion
Idunn's Apple Age-Defying Lotion was compared against 6 other popular top brands based on performance index (Function/Hazard Score).
Cream
Idunn's Apple Age-Defying Night Cream was compared against 6 other popular top brands based on performance index (Function/Hazard Score).
Resources
Skin Concerns
In skincare, the most common concerns include skin aging, loss of firmness and elasticity, reduced moisture retention, sun damage, ROS-induced oxidation, sensitivity, and pigmentation. Among these, skin aging and ROS-caused oxidation are particularly significant. They can lead to an increased risk of skin diseases such as acne, accelerated loss of collagen and elastin (resulting in wrinkles), increased DNA damage, heightened skin sensitivity, and enhanced skin pigmentation.
Skin Types
The skin, being the largest organ of the body, is classified into five major types by the American Academy of Dermatology (AAD): dry, oily, normal, combination, and sensitive. Each type possesses unique characteristics and is primarily influenced by epigenetics. Epigenetic regulation, which can be modified through environmental interactions, is a key determinant of your skin type, health, and beauty. This makes skin changes dynamic and reversible.
Skin Epigenetics
Skin Epigenetics involves the study of biological mechanisms that switch genes on or off in the skin. Since genes provide instructions for the production of functional proteins within cells, epigenetic mechanisms like DNA methylation affect how cells read genes and decide whether to produce specific proteins. For instance, although the COL1A1 gene exists in all cell types, it's "expressed" in skin cells to produce Type 1 Collagen proteins. While natural epigenetic changes occur with aging, external factors such as pollutants, smoking, exercise, diet, and sleep also have significant impacts. Skincare products typically contain active ingredients that can influence these epigenetic factors, affecting various aspects of skin quality.
Active Ingredients
An active ingredient in skincare products is one that has a biological effect, such as slowing skin aging, improving firmness and elasticity, balancing moisture retention, protecting from sun damage, reducing ROS-caused oxidation, preventing sensitivity, and decreasing pigmentation. Safe and effective active ingredients include L-ascorbic acid, hyaluronic acid, Vitamin E, ceramide, niacinamide, glycerin, tea polyphenol, and short peptides.
Clean Skincare
Clean skincare refers to products free from harmful chemicals or hazardous ingredients. Such ingredients include parabens, phthalates, sulfates, synthetic fragrances, and others scored at level 3-10 by the Environmental Working Group (EWG). Awareness of the potential risks associated with these ingredients is growing, and they are increasingly being avoided in clean skincare products.
Skin Anti-Aging Tests
Typically, skin anti-aging levels are determined in labs using expensive equipment and DNA samples, often requiring several weeks for results. Epigencare, a New York-based biotechnology company, has developed Skintelli, a rapid self-test for skin anti-aging/anti-oxidant levels. This test is simple, convenient, and can be performed at home in under 10 minutes. Understanding your skin’s natural anti-aging/anti-oxidant levels and how they are affected by skincare products is crucial for maintaining skin health and combating aging. Skintelli provides clear insights into the most suitable skincare products for your needs.
Frequently Asked Questions
What is Idunn’s Apple Skincare?
Idunn’s Apple is a personalized skincare brand that focuses on scientifically-backed, epigenetically proven formulations. Our products are tailored to target both the intrinsic and extrinsic causes of aging, helping to rejuvenate skin and reverse signs of aging at the cellular level.
How does Idunn’s Apple target the root causes of aging?
Idunn’s Apple uses a unique blend of active ingredients targeting three key areas:
- DNA Demethylation – Green tea compounds promote DNA demethylation, activating skin stem cells and boosting collagen synthesis.
- Collagen Peptides – Sourced from deep-sea shark bones, these peptides enhance the integration and production of collagen.
- Antioxidant Defense – Our balanced oxidant-defying compounds neutralize harmful ROS, protect mitochondria, and stabilize skin cells for long-lasting youthfulness.
How does Idunn’s Apple personalize my skincare routine?
Idunn’s Apple uses a combination of AI-driven technology and epigenetic data to assess your skin’s biological age, lifestyle, and environmental factors. Based on this analysis, we create a skincare routine tailored specifically to your skin’s unique needs.
What is the ultimate goal of Idunn’s Apple?
The ultimate goal of Idunn’s Apple is to reverse skin aging at its core by targeting both the intrinsic and extrinsic factors that cause aging. By promoting collagen synthesis, protecting against oxidative damage, and restoring mitochondrial function, we aim to give you visibly younger, healthier skin.
How does Idunn’s Apple work to reverse aging?
Our formulas are designed to tackle aging from the inside out. By promoting collagen synthesis, reducing oxidative stress, and rejuvenating skin stem cells, Idunn’s Apple actively restores skin’s youthful state. The product contains:
- Green Tea Extracts for activating DNA demethylation.
- Collagen Peptides for enhancing collagen production.
- Antioxidants for preventing and repairing ROS damage.
What are the visible results of using Idunn’s Apple products?
With consistent use, you’ll experience:
- Smoother, firmer skin.
- Reduced wrinkles and fine lines.
- Increased skin elasticity and hydration.
- Improved texture and a more youthful appearance.
When will I see results?
You’ll start noticing significant improvements within 2 weeks of regular application. Over time, you’ll see continuous improvements in skin texture, firmness, and overall radiance.
What is the fundamental cause of skin aging?
Skin aging is driven by both extrinsic and intrinsic factors. Extrinsic aging results from environmental damage, primarily oxidative stress caused by ROS (reactive oxygen species) from UV radiation and pollution. Intrinsic aging is due to cell degeneration and mitochondrial dysfunction, which impede the skin’s ability to regenerate. Epigenetic dysregulation is a key factor in intrinsic aging, as it affects cell generation and mitochondrial health.
What are the cellular and tissue changes that cause skin aging?
Skin aging starts with thinning of the epidermis, abnormal basal keratinocyte function, and breakdown of the dermal-epidermal junction. In the dermis, the extracellular matrix (ECM) degrades, with collagen and elastin either breaking down or becoming disorganized, leading to sagging, wrinkles, and decreased elasticity.
What are the visible signs of skin aging?
Common signs of skin aging include wrinkles, sagging skin, eye bags, skin roughness, nasolabial folds, and dark spots. These are caused by changes in both skin cells and tissue, such as collagen degradation and loss of skin elasticity.
How can skin aging be slowed or reversed?
To slow or reverse skin aging, it's important to prevent oxidative damage externally and promote cell regeneration internally. Epigenetic regulation, mitochondrial health, and collagen synthesis all play a crucial role. Idunn’s Apple targets these areas, restoring skin’s youthful state at the cellular level.
Are the ingredients safe?
All ingredients used in Idunn’s Apple are clinically graded, epigenetically proven, and free from harsh chemicals. We prioritize safety and efficacy to deliver visible, long-term results.
How should I use Idunn’s Apple products?
For the best results, apply Idunn’s Apple products daily as part of your skincare routine. Our Age-Defying Day Lotion and serums are designed for consistent use, delivering anti-aging benefits over time.
Why should I choose Idunn’s Apple?
Unlike other skincare products, Idunn’s Apple targets aging at its biological roots, using science-backed formulations to deliver real, lasting results. Our approach addresses not just the surface of the skin, but the deeper cellular causes of aging.